刘龙华
1.个人基本信息
刘龙华，1987年12月生，上海体育大学 副教授，上海市青年领军人才（海外），硕导，哥伦比亚大学博士后。主要从事运动与肥胖、糖尿病及动脉粥样硬化等慢性疾病的分子机制研究，并进行相应的药物开发。目前为止，共发表学术文章或专著25篇 （其中SCI论文：20篇），H因子：15，以第一作者或通讯作者发表在 Diabetes (IF2021=9.337, 中科院1区顶刊)；ATVB （IF2021=10.514，中科院1区顶刊）；Cell death and disease (IF2021=9.685，中科院1区顶刊); Cellular and Molecular Life Sciences. (IF2021=9.207，中科院1区顶刊)；Oxidative Medicine and Cellular longevity (IF2021=7.310，中科院2区)等国际知名期刊上13篇。担任中国生物物理学会代谢生物学分会青年委员，中国营养学会运动营养分会委员，担任 Frontiers in Physiology 审稿编辑，Acta Pharmaceutica Sinica B, Cellular& Molecular Biology, Journal of Cellular and Molecular Medicine 等国际期刊的审稿专家。
联系方式：195xxxx4590，liulonghua@sus.edu.cn.
2.教育和工作经历
2020.8-至今 上海体育大学 运动科学学院 副教授
2017.2-2020.6, 哥伦比亚大学 (Columbia University) , 病理与细胞生物学, 博士后
2013.8-2016.12 弗吉尼亚理工大学 (Virginia Tech), 人类营养与健康， 博士
2010.9-2013.7， 清华大学， 生物学 硕士
2006.9—2010.7 北京交通大学， 生物医学工程， 本科
3. 主要项目与荣誉
2022.01-2024.12 上海市青年领军人才（海外）
2023年第一届上海市运动健康科普奖一等奖 图书类作品《儿童青少年肥胖防控手册》，副主编。
4. 主要学术成果
1.Longhua Liu1; Lihong Fan1; Michelle Chan; Michael J. Kraakman; Jing Yang; Yong Fan; Nikki Aaron; Qianfen Wan; Maria Alicia Carrillo-Sepulveda; Alan R Tall, Ira Tabas, Domenico Accili and Li Qiang*. PPARg deacetylation confers the antiatherogenic effect and improves endothelial function in diabetes treatment. Diabetes. 2020; 69:1793-1803. ( IF2021=9.337, 中科院1区顶刊,被引：20)
2.Tarik Zahr1, 2*, Longhua Liu1, 3*，Michelle Chan1, Qiuzhong Zhou4, Bishuang Cai5, Ying He1,3, Nicole Aaron1,2, Ira Tabas6, Domenico Accili1, 6, Lei Sun4, Li Qiang1,3†. PPARgamma Deacetylation Suppresses Hypercholesterolemia and Aging-Associated Atherosclerosis. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2023 Jan;43(1):30-44DOI: 10.1161/ATVBAHA.122.318061 ( IF2021=10.514, 中科院1区顶刊，被引：6)
3.Shi, Z.; Wang, L.; Luan, J.; Yin, L.; Ji, X.; Zhang, W.; Xu, B.; Chen, L.; He, Y.; Wang, R*.; Liu, L.*. Exercise Promotes Bone Marrow Microenvironment by Inhibiting Adipsin in Diet-Induced Male Obese Mice. Nutrients 2023, 15, 19. https://doi.org/10.3390/nu15010019（IF2022=5.9, 中科院2区顶刊）
4.Longhua Liu1, Michelle Chan1, Lexiang Yu, Weidong Wang, Li Qiang*. Adipsin deficiency does not impact atherosclerosis development in Ldlr-/- mice. American Journal of Physiology Endocrinology and Metabolism2021. (1: co-first authors) (IF2021=5.900, JCR1区，被引：10).
5.Longhua Liu1*, Zunhan Shi1, Xiaohui Ji, Wenqian Zhang, Jinwen Luan, Tarik Zahr, Li Qiang*. Adipokines, adiposity, and atherosclerosis. Cellular and Molecular Life Sciences. (IF2022=8, 中科院1区顶刊).2022. 79 (5), 1-18. (一作，共通讯，中科院1区顶刊，被引：36)
6.Maria Namwanje1, Longhua Liu1, Michelle Chan, Nikki Aaron, Michael J. Kraakman, Li Qiang*. The depot-specific and essential roles of CBP/p300 in regulating adipose plasticity. Journal of Endocrinology 2019; 240 (2):257-269 （IF2019=4.041, 中科院二区，被引：16次）
7.Xiaohui Ji † , Wenqian Zhang †, Liqin Yin , Zunhan Shi, Jinwen Luan, Linshan Chen and Longhua Liu *. The Potential Roles of Post-Translational Modifications of PPARg in Treating Diabetes. Biomolecules 2022, 12, 1832. https://doi.org/10.3390/biom12121832. (IF2021=6.064, 中科院2区，被引：8)
8.Liqin Yin, Lihui Wang, Zunhan Shi, Xiaohui Ji, Longhua Liu*. The Role of Peroxisome Proliferator-Activated Receptor Gamma and Atherosclerosis: Post-translational Modification and Selective Modulators. Frontiers in Physiology. (IF2021=4.755, 中科院二区顶刊，被引：8).
9.Jinwen Luan†, Xiaohui Ji †, Longhua Liu *. PPARγ in atherosclerotic endothelial dysfunction: regulatory compounds and PTMs. International Journal of molecular sciences 2023,24，14494. DOI:10.3390/ijms241914494 (IF2022=5.6, 中科院 2区 A2)
10.Linshan Chen, Longhua Liu*. Adipose thermogenic mechanisms by cold, exercise and intermittent fasting: Similarities, disparities and the application in treatment. Clinical Nutrition. 2024 Sep;43(9):2043-2056. doi: 10.1016/j.clnu.2024.07.024. (IF2023=6.6, 中科院 2区 A2).
11.L Liu, P Zou, L Zheng, L E Linarelli, S Amarell, A Passaro, D Liu and Z Cheng*. Tamoxifen Reduces Fat Mass by Boosting Reactive Oxygen Species. Cell Death and Disease 2015; 6, e1586 （IF2021=9.685, 中科院1区顶刊，被引：70次）
12.Longhua Liu, Zhipeng Tao, Louise D Zheng, Joseph P Brooke, Cayleen M Smith, Dongmin Liu, Yun Chau Long and Zhiyong Cheng*. FoxO1 interacts with transcription factor EB and differentially regulates mitochondrial uncoupling proteins via autophagy in adipocytes. Cell Death Discovery (2016.10) 2, 16066. （IF2021=7.109, 中科院二区, 被引：48次）
13.L Liu, L Zheng, P Zou, J Brooke, C Smith, YC Long, F Almeida, D Liu and Z Cheng*. FoxO1 antagonist suppresses autophagy and lipid droplet growth in adipocytes. Cell Cycle 2016; 15:2033-41; PMID: 27260854 DOI: 10.1080/ 15384101. 2016. 1192732. （IF2021=5.173, JCR 2区, 被引：52次）
14.P Zou1, L Liu1, L Zheng, K Payne, M Manjili, M Idowu, J Zhang, E Schmelz, Z Cheng*. Coordinated upregulation of mitochondrial biogenesis and turnover in breast cancer cells: the role of dynamin related protein-1 and implication for breast cancer treatment. Oxidative Medicine and Cellular Longevity 2016: 4085727 （IF2021=7.310, 中科院二区, 被引：40次）
15.Zou P1, Liu L1, Zheng L, Liu L, Stoneman RE, Cho A, Emery A, Gilbert ER, Cheng Z*. Targeting FoxO1 with AS1842856 Suppresses Adipogenesis. Cell Cycle 2014;13:3759-67. （共一，IF2021=5.173, JCR 2区, 被引：80次）
16.Liu LH, Xie JY, Guo WW, Wu GY, Chen ZF, Yi JY, Zhang L, Zhang ZJ, Li Z*. Evodiamine activates AMPK and promotes adiponectin multimerization in 3T3-L1 adipocytes. J Asian Nat Prod Res. 2014; 16:1074-83. ( JCR 3区, 被引：18次 )
17.Liu L, Zheng LD, Donnelly SR, Emont MP, Wu J, Cheng Z. Isolation of Mouse Stromal Vascular Cells for Monolayer Culture. Methods Mol Biol. 2017;1566:9-16.
18.Liu L., Cheng Z. Forkhead Box O (FoxO) Transcription Factors in Autophagy, Metabolic Health, and Tissue Homeostasis. In: Turksen K. (eds) Autophagy in Health and Disease. Stem Cell Biology and Regenerative Medicine. 2018.Humana Press, Cham.
19.L Zheng, L Linarelli, L Liu, S Wall, M Greenawald, R Seidel, P Estabrooks, F Almeida* and Z Cheng*. Insulin resistance is associated with epigenetic and genetic regulation of mitochondrial DNA in obese humans. Clinical Epigenetics. 2015; 7:60.
20.Tao Z, Liu L, Zheng LD, Cheng Z. Autophagy in Adipocyte Differentiation. Methods Mol Biol. 2017 Aug 17. doi: 10.1007/7651_2017_65.
21.M Chan, YC Lim, J Yang, M Namwanje, L Liu, L Qiang. Identification of a natural beige adipose depot in mice. Journal of Biological Chemistry.2019. jbc. RA118. 006838
